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  1. Free, publicly-accessible full text available February 13, 2025
  2. Abstract

    Close binary systems present challenges to planet formation. As binary separations decrease, so do the occurrence rates of protoplanetary disks in young systems and planets in mature systems. For systems that do retain disks, their disk masses and sizes are altered by the presence of the binary companion. Through the study of protoplanetary disks in binary systems with known orbital parameters, we seek to determine the properties that promote disk retention and therefore planet formation. In this work, we characterize the young binary−disk system FO Tau. We determine the first full orbital solution for the system, finding masses of0.350.05+0.06Mand 0.34 ± 0.05Mfor the stellar components, a semimajor axis of22(1+2)au, and an eccentricity of0.21(0.03+0.04). With long-baseline Atacama Large Millimeter/submillimeter Array interferometry, we detect 1.3 mm continuum and12CO (J= 2–1) line emission toward each of the binary components; no circumbinary emission is detected. The protoplanetary disks are compact, consistent with being truncated by the binary orbit. The dust disks are unresolved in the image plane, and the more extended gas disks are only marginally resolved. Fitting the continuum and CO visibilities, we determine the inclination of each disk, finding evidence for alignment of the disk and binary orbital planes. This study is the first of its kind linking the properties of circumstellar protoplanetary disks to a precisely known binary orbit. In the case of FO Tau, we find a dynamically placid environment (coplanar, low eccentricity), which may foster its potential for planet formation.

     
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  3. Free, publicly-accessible full text available December 13, 2024
  4. Abstract

    Decades of advances in understanding and simulating the polymerization kinetics and structural evolution that arises in free‐radical photopolymerizations of multifunctional monomers are combined into a single, first‐principles 3D model. The model explicitly accounts for polymerization features including diffusion‐controlled kinetics, oxygen inhibition, light attenuation, chain‐length dependent termination, reaction‐diffusion termination, heat transfer, composition and conversion‐dependent material properties, crosslinking effects, and species diffusion. Using the homopolymerization of 1,6‐hexanediol diacrylate as a model system, a minimum of two kinetics experiments performed at different initiation rates are required to fit model parameters. The model accurately predicts known relationships regarding oxygen inhibition, light intensity, and curing temperature for samples of different geometries and boundary conditions. The emphasis of the results herein is placed on the interactions between polymerization features, motivating the importance of a model that accommodates these features all in one simulation. The model is shown to be robust in its handling of thermal boundary conditions, alternative polymerization techniques or mechanisms, and characteristics of 3D voxel formation. The model in this work provides a useful tool for property prediction in a wide variety of applications, most notably coatings, dental materials, industrial photocuring processes, additive manufacturing, and holography, where complex interactions of the various features of polymerization play a substantial role.

     
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  5. Free, publicly-accessible full text available September 1, 2024
  6. Free, publicly-accessible full text available November 1, 2024
  7. Single-cell genomic technologies offer vast new resources with which to study cells, but their potential to inform parameter inference of cell dynamics has yet to be fully realized. Here we develop methods for Bayesian parameter inference with data that jointly measure gene expression and Ca2+dynamics in single cells. We propose to share information between cells via transfer learning: for a sequence of cells, the posterior distribution of one cell is used to inform the prior distribution of the next. In application to intracellular Ca2+signalling dynamics, we fit the parameters of a dynamical model for thousands of cells with variable single-cell responses. We show that transfer learning accelerates inference with sequences of cells regardless of how the cells are ordered. However, only by ordering cells based on their transcriptional similarity can we distinguish Ca2+dynamic profiles and associated marker genes from the posterior distributions. Inference results reveal complex and competing sources of cell heterogeneity: parameter covariation can diverge between the intracellular and intercellular contexts. Overall, we discuss the extent to which single-cell parameter inference informed by transcriptional similarity can quantify relationships between gene expression states and signalling dynamics in single cells.

     
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    Free, publicly-accessible full text available June 1, 2024
  8. A thin Smectic-A liquid crystal (LC) film is deposited on a polymer vinyl alcohol-coated substrate that had been scribed with a uniform easy axis pattern over a square of side length L ≤ 85 μm. The small size of the patterned region facilitates material distribution to form either a hill (for a thin film) or divot (for a thick film) above the scribed square and having an oily streak (OS) texture. Optical profilometry measurements vs. film thickness suggest that the OS structure aims to adopt a preferred thickness z 0 that depends on the nature of the molecule, the temperature, and the surface tension at the air interface. We present a phenomenological model that estimates the energy cost of the OS layer as its thickness deviates from z 0 . 
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    Free, publicly-accessible full text available May 24, 2024
  9. A thin Smectic-A liquid crystal (LC) film is deposited on a polymer vinyl alcohol-coated substrate that had been scribed with a uniform easy axis pattern over a small square of dimensions side L < 85 um. Because of the small size of the patterned region facilitates material distribution to form either a hill (for a thin film) or divot (for a thick film) above the scribed square, which that exhibits an oily streak (OS) texture. Optical profilometry measurements vs. film thickness suggest that the OS structure aims to adopt a preferred thickness z0 that depends on the nature of the molecule, the temperature, and the surface tension at the air interface. We present a phenomenological model that estimates the energy cost of the OS layer as its thickness deviates from z0. 
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    Free, publicly-accessible full text available May 9, 2024
  10. Abstract

    The dispersed remnants of stellar nurseries, stellar associations, provide unparalleled samples of coeval stars critical for studies of stellar and planetary formation and evolution. The Carina Stellar Association is one of the closest stellar associations to Earth, and yet measurements of its age have varied from 13 to 45 Myr. We aim to update the age of Carina using the lithium depletion boundary (LDB) method. We obtain new measurements of the Li 6708 Å absorption feature in likely members using optical spectra from the Goodman High Throughput Spectrograph on SOAR and NRES on LCO. We detect the depletion boundary atMK≃ 6.8 (M5). This age is consistent within uncertainties across six different models, including those that account for magnetic fields and spots. We also estimate the age through analysis of the group’s overall variability, and by comparing the association members’ color–magnitude diagram to stellar evolutionary models using a Gaussian Mixture Model, recovering ages consistent with the LDB. Combining these age measures we obtain an age for the Carina association of415+3Myr. The resulting age agrees with the older end of previous age measurements and is consistent with the lithium depletion age for the neighboring Tucana-Horologium moving group.

     
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